Disease: Impaired cognition
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ST3GAL5 Q9UNP4 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.3E-03 0.650 0.654
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SMS P52788 spermine synthase 0.97 0.491 0.846
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
SLC18A3 Q16572 solute carrier family 18 member A3 Transporter 0.45 0.608 0.654
SLC12A2 P55011 solute carrier family 12 member 2 Transporter 0.96 0.552 0.808
SIRT3 Q9NTG7 sirtuin 3 Epigenetic regulator 1.6E-04 0.488 0.731
SCN9A Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 4.8E-19 0.543 0.615
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
S1PR1 P21453 sphingosine-1-phosphate receptor 1 G-protein coupled receptor 0.73 0.546 0.769
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
RSS Russell Silver syndrome 0.578 0.692
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923