Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808