Disease: Malignant tumor of colon
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808