Disease: tumor vasculature
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885