Disease: Heroin Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AGBL4 Q5VU57 ATP/GTP binding protein like 4 Enzyme 2.5E-06 0.760 0.231
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PENK P01210 proenkephalin Signaling 2.1E-04 0.560 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TERC telomerase RNA component 0.471 0.846
ZNF804A Q7Z570 zinc finger protein 804A 5.5E-03 0.647 0.654