Disease: Cocaine Abuse
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615
CHRM5 P08912 cholinergic receptor muscarinic 5 G-protein coupled receptor 4.0E-03 0.769 0.346
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HCRTR1 O43613 hypocretin receptor 1 G-protein coupled receptor 1.7E-04 0.623 0.654
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
NPY2R P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 3.6E-02 0.612 0.577
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808