Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
HGF | P14210 | hepatocyte growth factor | Enzyme | 1.00 | 0.374 | 0.885 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |