Disease: Muscle Weakness Lower Limb
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
TPM3 P06753 tropomyosin 3 Cellular structure 6.7E-03 0.490 0.808
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
HADHA P40939 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Enzyme 4.4E-06 0.569 0.769
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
DYSF O75923 dysferlin Transporter 3.7E-33 0.582 0.692
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654