Disease: Distal amyotrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LMNA P02545 lamin A/C 1.00 0.384 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
VCP P55072 valosin containing protein 1.00 0.469 0.923
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
NEFL P07196 neurofilament light 0.488 0.769
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
MPZ P25189 myelin protein zero 0.27 0.503 0.846
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
FBLN5 Q9UBX5 fibulin 5 Calcium-binding protein 1.00 0.546 0.692
CHP1 Q99653 calcineurin like EF-hand protein 1 0.63 0.546 0.769
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769
SLC25A1 P53007 solute carrier family 25 member 1 Transporter 5.9E-02 0.553 0.731
ZBTB20 Q9HC78 zinc finger and BTB domain containing 20 0.97 0.566 0.731