Disease: Impaired vibration sensation in the lower limbs
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
FLRT1 Q9NZU1 fibronectin leucine rich transmembrane protein 1 0.36 0.780 0.231
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
HARS1 P12081 histidyl-tRNA synthetase 1 Enzyme 2.4E-06 0.569 0.808
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KLC2 Q9H0B6 kinesin light chain 2 0.98 0.736 0.346
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
PDK3 Q15120 pyruvate dehydrogenase kinase 3 Kinase 0.45 0.678 0.500
RTN2 O75298 reticulon 2 0.42 0.711 0.385
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
VAMP1 P23763 vesicle associated membrane protein 1 3.9E-03 0.628 0.538
VCP P55072 valosin containing protein 1.00 0.469 0.923
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615