Disease: Scoliosis, unspecified
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
DNAH5 Q8TE73 dynein axonemal heavy chain 5 Enzyme 4.9E-64 0.590 0.692
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
CDON Q4KMG0 cell adhesion associated, oncogene regulated 2.1E-15 0.601 0.731
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
TMEM94 Q12767 transmembrane protein 94 2.8E-14 0.628 0.654
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769
TDGF1 P13385 teratocarcinoma-derived growth factor 1 Calcium-binding protein 9.2E-11 0.584 0.731