Disease: Aortic coarctation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
GATA6 Q92908 GATA binding protein 6 1.00 0.478 0.808
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
PAH P00439 phenylalanine hydroxylase 6.4E-23 0.516 0.769
TBX5 Q99593 T-box transcription factor 5 Transcription factor 1.00 0.528 0.769
GDF1 P27539 growth differentiation factor 1 Signaling 0.41 0.529 0.692
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577
NR2F2 P24468 nuclear receptor subfamily 2 group F member 2 Nuclear receptor 0.99 0.575 0.692
GATA5 Q9BWX5 GATA binding protein 5 0.28 0.578 0.615