Disease: Thrombocythemia, Essential
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
DERL1 Q9BUN8 derlin 1 Receptor 2.1E-04 0.576 0.654
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692