Disease: Primary sclerosing cholangitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
AIRE O43918 autoimmune regulator 4.0E-12 0.516 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL25 O15444 C-C motif chemokine ligand 25 Signaling 1.5E-02 0.610 0.692
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CFLAR O15519 CASP8 and FADD like apoptosis regulator Enzyme 1.00 0.485 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846