Disease: MAJOR AFFECTIVE DISORDER 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADORA1 P30542 adenosine A1 receptor G-protein coupled receptor 1.5E-02 0.578 0.692
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NR4A3 Q92570 nuclear receptor subfamily 4 group A member 3 Nuclear receptor 0.91 0.502 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654