Disease: nervous system disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
PLB1 Q6P1J6 phospholipase B1 1.7E-72 0.488 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
MICU1 Q9BPX6 mitochondrial calcium uptake 1 Calcium-binding protein 1.9E-13 0.638 0.654
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
PMPCA Q10713 peptidase, mitochondrial processing subunit alpha Enzyme 3.4E-11 0.633 0.577