Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CDK5R1 Q15078 cyclin dependent kinase 5 regulatory subunit 1 Enzyme modulator 0.91 0.529 0.808
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GCG P01275 glucagon 3.5E-02 0.431 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
HTT P42858 huntingtin 1.00 0.548 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LAMP2 P13473 lysosomal associated membrane protein 2 Transporter 0.27 0.552 0.731
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808