Disease: Neurofibromatoses
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GNA12 Q03113 G protein subunit alpha 12 Enzyme modulator 0.97 0.547 0.769
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
H3P23 H3 histone pseudogene 23 0.443 0.769
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MEN1 O00255 menin 1 1.00 0.444 0.808
NES P48681 nestin 1.6E-06 0.450 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923