Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | |
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
COX8A | P10176 | cytochrome c oxidase subunit 8A | Enzyme | 0.12 | 0.400 | 0.846 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
MIR34A | microRNA 34a | 0.421 | 0.846 | |||
BAX | Q07812 | BCL2 associated X, apoptosis regulator | Signaling | 0.32 | 0.417 | 0.885 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
FASLG | P48023 | Fas ligand | Signaling | 0.18 | 0.430 | 0.885 |
ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 | |
S100A8 | P05109 | S100 calcium binding protein A8 | Calcium-binding protein | 0.14 | 0.430 | 0.962 |
MMP13 | P45452 | matrix metallopeptidase 13 | Enzyme | 7.9E-18 | 0.452 | 0.923 |
PGF | P49763 | placental growth factor | Signaling | 0.13 | 0.460 | 0.846 |
SMAD7 | O15105 | SMAD family member 7 | Transcription factor | 0.55 | 0.470 | 0.769 |
NRP1 | O14786 | neuropilin 1 | 0.99 | 0.476 | 0.808 | |
ATF3 | P18847 | activating transcription factor 3 | Transcription factor | 8.9E-02 | 0.494 | 0.885 |