Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769
IL12A P29459 interleukin 12A 4.7E-02 0.491 0.808
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
SAA1 P0DJI8 serum amyloid A1 Transporter 1.5E-02 0.513 0.808
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692