Disease: Thrombophilia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
F8 P00451 coagulation factor VIII Enzyme 1.00 0.542 0.769
F13A1 P00488 coagulation factor XIII A chain Enzyme 5.3E-08 0.575 0.731
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
F12 P00748 coagulation factor XII Enzyme 8.3E-08 0.612 0.577
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
SERPINC1 P01008 serpin family C member 1 Enzyme modulator 1.00 0.507 0.769
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769
FGB P02675 fibrinogen beta chain Signaling 0.57 0.584 0.692
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F11 P03951 coagulation factor XI Enzyme 3.6E-26 0.590 0.692
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
THBD P07204 thrombomodulin 5.4E-02 0.457 0.769
PROS1 P07225 protein S 4.7E-04 0.467 0.846
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
TFPI P10646 tissue factor pathway inhibitor Enzyme modulator 0.25 0.486 0.808
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923