Disease: Upward slant of palpebral fissure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
MCPH1 Q8NEM0 microcephalin 1 Nucleic acid binding 7.8E-30 0.540 0.846
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846
CEP152 O94986 centrosomal protein 152 Signaling 2.7E-27 0.653 0.500
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
WDR62 O43379 WD repeat domain 62 2.4E-23 0.597 0.615
CDK5RAP2 Q96SN8 CDK5 regulatory subunit associated protein 2 4.6E-23 0.682 0.577
CEP135 Q66GS9 centrosomal protein 135 Enzyme modulator 3.6E-22 0.695 0.615
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769
ANKLE2 Q86XL3 ankyrin repeat and LEM domain containing 2 1.0E-10 0.691 0.500
NCAPD3 P42695 non-SMC condensin II complex subunit D3 Nucleic acid binding 5.8E-09 0.722 0.423
SASS6 Q6UVJ0 SAS-6 centriolar assembly protein 1.7E-07 0.691 0.423
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
PYCR2 Q96C36 pyrroline-5-carboxylate reductase 2 2.1E-06 0.682 0.462
KIF14 Q15058 kinesin family member 14 Cellular structure 4.1E-05 0.578 0.654
MFSD2A Q8NA29 major facilitator superfamily domain containing 2A Transporter 1.1E-02 0.626 0.538
TAF13 Q15543 TATA-box binding protein associated factor 13 Nucleic acid binding 1.6E-02 0.716 0.385
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
MAP11 Q8WVR3 microtubule associated protein 11 0.18 0.736 0.423
STIL Q15468 STIL centriolar assembly protein 0.20 0.584 0.731
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769