Disease: Retinal Dystrophies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NR2E3 Q9Y5X4 nuclear receptor subfamily 2 group E member 3 Nuclear receptor 0.603 0.500
USH2A O75445 usherin Enzyme modulator 1.6E-94 0.579 0.692
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ABCA4 P78363 ATP binding cassette subfamily A member 4 Transporter 5.3E-48 0.493 0.769
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769
EYS Q5T1H1 eyes shut homolog 3.7E-41 0.631 0.538
MYO7A Q13402 myosin VIIA Cellular structure 1.6E-38 0.585 0.423
RPGRIP1 Q96KN7 RPGR interacting protein 1 Enzyme modulator 1.3E-23 0.553 0.654
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
PRPH P41219 peripherin 4.8E-14 0.623 0.462
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
IMPG2 Q9BZV3 interphotoreceptor matrix proteoglycan 2 Extracellular structure 2.8E-13 0.659 0.308
MERTK Q12866 MER proto-oncogene, tyrosine kinase Kinase 2.7E-11 0.531 0.692
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808
GUCY2D Q02846 guanylate cyclase 2D, retinal Kinase 6.5E-10 0.570 0.769
ARL13B Q3SXY8 ADP ribosylation factor like GTPase 13B 2.7E-09 0.631 0.538
CLRN1 P58418 clarin 1 1.7E-08 0.633 0.423
BBS12 Q6ZW61 Bardet-Biedl syndrome 12 2.3E-07 0.674 0.462
CDH23 Q9H251 cadherin related 23 3.2E-06 0.539 0.769
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731
AIPL1 Q9NZN9 aryl hydrocarbon receptor interacting protein like 1 Chaperone 1.2E-05 0.644 0.346
TST Q16762 thiosulfate sulfurtransferase Enzyme 7.9E-05 0.588 0.654
RBP3 P10745 retinol binding protein 3 1.1E-04 0.621 0.500
SRD5A3 Q9H8P0 steroid 5 alpha-reductase 3 2.5E-04 0.604 0.692