Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NR2E3 Q9Y5X4 nuclear receptor subfamily 2 group E member 3 Nuclear receptor 0.603 0.500
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
SPHK1 Q9NYA1 sphingosine kinase 1 Kinase 3.0E-07 0.480 0.808
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
EPHA2 P29317 EPH receptor A2 Kinase 1.1E-05 0.501 0.731
MERTK Q12866 MER proto-oncogene, tyrosine kinase Kinase 2.7E-11 0.531 0.692
GUCY2D Q02846 guanylate cyclase 2D, retinal Kinase 6.5E-10 0.570 0.769
PBK Q96KB5 PDZ binding kinase Kinase 1.2E-06 0.541 0.769
MARK2 Q7KZI7 microtubule affinity regulating kinase 2 Kinase 1.00 0.555 0.692
TTK P33981 TTK protein kinase Kinase 1.3E-03 0.555 0.731
MARK3 P27448 microtubule affinity regulating kinase 3 Kinase 1.4E-06 0.729 0.423
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CLCN7 P51798 chloride voltage-gated channel 7 Ion channel 0.27 0.590 0.731
TRPM1 Q7Z4N2 transient receptor potential cation channel subfamily M member 1 Ion channel 1.6E-42 0.626 0.462
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
ADGRG1 Q9Y653 adhesion G protein-coupled receptor G1 G-protein coupled receptor 5.3E-10 0.590 0.654
IMPG2 Q9BZV3 interphotoreceptor matrix proteoglycan 2 Extracellular structure 2.8E-13 0.659 0.308
IMPG1 Q17R60 interphotoreceptor matrix proteoglycan 1 Extracellular structure 1.4E-29 0.722 0.154
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846