Disease: Hyperammonemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SLC7A7 Q9UM01 solute carrier family 7 member 7 Transporter 8.0E-07 0.603 0.654
SLC25A13 Q9UJS0 solute carrier family 25 member 13 Transporter 1.3E-24 0.617 0.500
MCCC2 Q9HCC0 methylcrotonoyl-CoA carboxylase 2 Enzyme 4.5E-11 0.674 0.423
ATP6V0A4 Q9HBG4 ATPase H+ transporting V0 subunit a4 Transporter 2.2E-20 0.722 0.385
MCCC1 Q96RQ3 methylcrotonoyl-CoA carboxylase 1 Enzyme 4.0E-12 0.700 0.308
MMAB Q96EY8 metabolism of cobalamin associated B Enzyme 4.1E-03 0.695 0.538
NAGS Q8N159 N-acetylglutamate synthase 4.0E-08 0.716 0.423
MMAA Q8IVH4 metabolism of cobalamin associated A 9.4E-13 0.743 0.346
HADH Q16836 hydroxyacyl-CoA dehydrogenase 6.6E-05 0.650 0.538
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
NDUFA6 P56556 NADH:ubiquinone oxidoreductase subunit A6 Enzyme 1.3E-04 0.711 0.346
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
HLCS P50747 holocarboxylase synthetase Enzyme 1.9E-08 0.650 0.654
ACADVL P49748 acyl-CoA dehydrogenase very long chain Enzyme 4.2E-15 0.653 0.654
BTD P43251 biotinidase Enzyme 1.5E-07 0.628 0.654
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
HMGCL P35914 3-hydroxy-3-methylglutaryl-CoA lyase Enzyme 2.6E-06 0.691 0.462
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CPS1 P31327 carbamoyl-phosphate synthase 1 Enzyme 1.1E-09 0.590 0.615
ACADL P28330 acyl-CoA dehydrogenase long chain Enzyme 1.7E-12 0.736 0.462
IVD P26440 isovaleryl-CoA dehydrogenase Enzyme 1.5E-14 0.705 0.462
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769
MMUT P22033 methylmalonyl-CoA mutase Enzyme 1.7E-22 0.534 0.731
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923