Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
ADIPOQ | Q15848 | adiponectin, C1Q and collagen domain containing | 4.6E-09 | 0.376 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
AHR | P35869 | aryl hydrocarbon receptor | Transcription factor | 1.00 | 0.410 | 0.923 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
DRD2 | P14416 | dopamine receptor D2 | G-protein coupled receptor | 0.75 | 0.436 | 0.846 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
LEPR | P48357 | leptin receptor | Signaling | 0.99 | 0.433 | 0.808 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
CFH | P08603 | complement factor H | 0.86 | 0.441 | 0.885 | |
CNR1 | P21554 | cannabinoid receptor 1 | G-protein coupled receptor | 0.51 | 0.446 | 0.808 |
GDF15 | Q99988 | growth differentiation factor 15 | Signaling | 3.0E-07 | 0.429 | 0.808 |
STS | P08842 | steroid sulfatase | Enzyme | 0.81 | 0.431 | 0.846 |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | |
CD36 | P16671 | CD36 molecule | Receptor | 1.1E-60 | 0.446 | 0.846 |