Disease: Fanconi Anemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
DNA2 P51530 DNA replication helicase/nuclease 2 1.3E-18 0.626 0.731
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
NEIL1 Q96FI4 nei like DNA glycosylase 1 5.0E-07 0.623 0.769
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
FEN1 P39748 flap structure-specific endonuclease 1 Enzyme 4.8E-05 0.550 0.731
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923