Disease: Bloom Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
DNA2 P51530 DNA replication helicase/nuclease 2 1.3E-18 0.626 0.731
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
FEN1 P39748 flap structure-specific endonuclease 1 Enzyme 4.8E-05 0.550 0.731
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
HFM1 A2PYH4 helicase for meiosis 1 4.7E-32 0.659 0.615
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD54L Q92698 RAD54 like 2.4E-15 0.633 0.423
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962