Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
POLQ O75417 DNA polymerase theta Enzyme 1.3E-82 0.695 0.462
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
POLH Q9Y253 DNA polymerase eta 3.5E-09 0.663 0.462
TERF2 Q15554 telomeric repeat binding factor 2 0.99 0.541 0.731
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
XRCC6P5 X-ray repair cross complementing 6 pseudogene 5 0.579 0.769