Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846