Disease: Xeroderma Pigmentosum, Complementation Group D
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
GTF2H2 Q13888 general transcription factor IIH subunit 2 Transcription factor 1.6E-02 0.650 0.577
GTF2H3 Q13889 general transcription factor IIH subunit 3 Nucleic acid binding 3.0E-08 0.656 0.615
GTF2H4 Q92759 general transcription factor IIH subunit 4 Transcription factor 4.2E-07 0.573 0.846
GTF2H5 Q6ZYL4 general transcription factor IIH subunit 5 4.5E-02 0.556 0.769
HFM1 A2PYH4 helicase for meiosis 1 4.7E-32 0.659 0.615
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
NR1H2 P55055 nuclear receptor subfamily 1 group H member 2 Nuclear receptor 0.38 0.533 0.769
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PDIK1L Q8N165 PDLIM1 interacting kinase 1 like Kinase 0.26 0.534 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962