Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
POLH Q9Y253 DNA polymerase eta 3.5E-09 0.663 0.462
POLQ O75417 DNA polymerase theta Enzyme 1.3E-82 0.695 0.462
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
TERF2 Q15554 telomeric repeat binding factor 2 0.99 0.541 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
XRCC6P5 X-ray repair cross complementing 6 pseudogene 5 0.579 0.769