Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NAT1 P18440 N-acetyltransferase 1 Enzyme 1.9E-14 0.536 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846
XRCC6P5 X-ray repair cross complementing 6 pseudogene 5 0.579 0.769