Disease: Trichothiodystrophy Syndromes
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CCNH P51946 cyclin H Enzyme modulator 8.1E-04 0.595 0.769
CDK7 P50613 cyclin dependent kinase 7 Kinase 4.5E-07 0.566 0.731
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
GTF2H2 Q13888 general transcription factor IIH subunit 2 Transcription factor 1.6E-02 0.650 0.577
GTF2H3 Q13889 general transcription factor IIH subunit 3 Nucleic acid binding 3.0E-08 0.656 0.615
GTF2H4 Q92759 general transcription factor IIH subunit 4 Transcription factor 4.2E-07 0.573 0.846
GTF2H5 Q6ZYL4 general transcription factor IIH subunit 5 4.5E-02 0.556 0.769
H3P33 H3 histone pseudogene 33 0.736 0.346
IFI44 Q8TCB0 interferon induced protein 44 1.9E-15 0.678 0.538
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808
NR1H2 P55055 nuclear receptor subfamily 1 group H member 2 Nuclear receptor 0.38 0.533 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
WDR77 Q9BQA1 WD repeat domain 77 2.5E-04 0.695 0.423
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808