Disease: Congenital ichthyosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
ALDH3A2 P51648 aldehyde dehydrogenase 3 family member A2 9.4E-06 0.619 0.769
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
CAPN12 Q6ZSI9 calpain 12 Enzyme 1.2E-33 0.890 0.077
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308
CST6 Q15828 cystatin E/M 0.37 0.612 0.615
CYB5A P00167 cytochrome b5 type A Enzyme 1.6E-03 0.601 0.654
CYP4F22 Q6NT55 cytochrome P450 family 4 subfamily F member 22 Enzyme 5.3E-06 0.705 0.462
DMKN Q6E0U4 dermokine 8.3E-13 0.729 0.308
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
FLG P20930 filaggrin Cellular structure 2.9E-04 0.525 0.846
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
LOX P28300 lysyl oxidase 0.99 0.447 0.846
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423
PNPLA1 Q8N8W4 patatin like phospholipase domain containing 1 Enzyme 1.9E-04 0.700 0.423
SDR9C7 Q8NEX9 short chain dehydrogenase/reductase family 9C member 7 Enzyme 1.2E-02 0.695 0.538
SLC27A4 Q6P1M0 solute carrier family 27 member 4 Transporter 4.5E-05 0.608 0.769
SPINK5 Q9NQ38 serine peptidase inhibitor Kazal type 5 Enzyme modulator 4.8E-28 0.604 0.654
ST14 Q9Y5Y6 suppression of tumorigenicity 14 Enzyme 0.56 0.514 0.769
STS P08842 steroid sulfatase Enzyme 0.81 0.431 0.846
SULT2B1 O00204 sulfotransferase family 2B member 1 0.44 0.641 0.538