Disease: Congenital arteriovenous malformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
PCYT1A P49585 phosphate cytidylyltransferase 1, choline, alpha 2.0E-05 0.485 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RFWD3 Q6PCD5 ring finger and WD repeat domain 3 Enzyme 3.5E-10 0.569 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885