Disease: Splenomegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAN2B1 O00754 mannosidase alpha class 2B member 1 4.8E-22 0.674 0.462
GNPTAB Q3T906 N-acetylglucosamine-1-phosphate transferase subunits alpha and beta 7.7E-19 0.592 0.731
GAA P10253 glucosidase alpha, acid Enzyme 2.8E-18 0.631 0.577
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
ASAH1 Q13510 N-acylsphingosine amidohydrolase 1 Enzyme 1.3E-12 0.526 0.808
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
ARSB P15848 arylsulfatase B 7.0E-09 0.595 0.692
NAGLU P54802 N-acetyl-alpha-glucosaminidase 1.4E-08 0.546 0.769
SUMF1 Q8NBK3 sulfatase modifying factor 1 2.3E-08 0.641 0.538
FUCA1 P04066 alpha-L-fucosidase 1 2.7E-08 0.623 0.577
GUSB P08236 glucuronidase beta 4.0E-08 0.530 0.846
SLC29A3 Q9BZD2 solute carrier family 29 member 3 Transporter 1.3E-07 0.578 0.769
LIPA P38571 lipase A, lysosomal acid type Enzyme 5.5E-07 0.564 0.654
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
AGA P20933 aspartylglucosaminidase Enzyme 4.3E-06 0.570 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
DNASE1L3 Q13609 deoxyribonuclease 1 like 3 3.0E-05 0.575 0.769
NEU1 Q99519 neuraminidase 1 Enzyme 7.3E-05 0.513 0.769
SGSH P51688 N-sulfoglucosamine sulfohydrolase Enzyme 1.0E-04 0.638 0.692
CTNS O60931 cystinosin, lysosomal cystine transporter 3.1E-04 0.628 0.538
GNS P15586 glucosamine (N-acetyl)-6-sulfatase Enzyme 5.6E-04 0.705 0.538
NPC2 P61916 NPC intracellular cholesterol transporter 2 1.8E-03 0.612 0.769