Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
CLCN6 | P51797 | chloride voltage-gated channel 6 | Ion channel | 6.1E-08 | 0.769 | 0.231 |
GNPTAB | Q3T906 | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta | 7.7E-19 | 0.592 | 0.731 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
IDS | P22304 | iduronate 2-sulfatase | 0.95 | 0.559 | 0.769 | |
IDUA | P35475 | alpha-L-iduronidase | Enzyme | 3.8E-13 | 0.499 | 0.846 |
MFSD8 | Q8NHS3 | major facilitator superfamily domain containing 8 | 2.5E-12 | 0.682 | 0.231 | |
MPEG1 | Q2M385 | macrophage expressed 1 | 3.6E-16 | 0.575 | 0.731 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NAGLU | P54802 | N-acetyl-alpha-glucosaminidase | 1.4E-08 | 0.546 | 0.769 | |
NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | Transporter | 6.5E-06 | 0.518 | 0.692 |
PIP4K2A | P48426 | phosphatidylinositol-5-phosphate 4-kinase type 2 alpha | Kinase | 0.14 | 0.647 | 0.423 |
PLP1 | P60201 | proteolipid protein 1 | Cellular structure | 0.93 | 0.543 | 0.769 |
PRKAA1 | Q13131 | protein kinase AMP-activated catalytic subunit alpha 1 | Kinase | 0.14 | 0.453 | 0.846 |
PRKAA2 | P54646 | protein kinase AMP-activated catalytic subunit alpha 2 | Kinase | 3.5E-08 | 0.456 | 0.846 |
PRKAB1 | Q9Y478 | protein kinase AMP-activated non-catalytic subunit beta 1 | Kinase | 5.3E-03 | 0.460 | 0.846 |
RPS27 | P42677 | ribosomal protein S27 | Nucleic acid binding | 0.76 | 0.578 | 0.769 |
SGSH | P51688 | N-sulfoglucosamine sulfohydrolase | Enzyme | 1.0E-04 | 0.638 | 0.692 |
SMPD1 | P17405 | sphingomyelin phosphodiesterase 1 | Enzyme | 3.9E-10 | 0.499 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TTK | P33981 | TTK protein kinase | Kinase | 1.3E-03 | 0.555 | 0.731 |