Disease: Venous Thrombosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
F12 P00748 coagulation factor XII Enzyme 8.3E-08 0.612 0.577
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
F7 P08709 coagulation factor VII Enzyme 1.3E-05 0.623 0.615
FGB P02675 fibrinogen beta chain Signaling 0.57 0.584 0.692
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
P2RY12 Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 1.7E-03 0.533 0.731
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808
SAA1 P0DJI8 serum amyloid A1 Transporter 1.5E-02 0.513 0.808
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962