Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
IFNA1 | P01562 | interferon alpha 1 | 0.371 | 0.923 | ||
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
IFNA13 | P01562 | interferon alpha 13 | 0.374 | 0.923 | ||
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
AHSA1 | O95433 | activator of HSP90 ATPase activity 1 | 1.00 | 0.396 | 0.923 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |