Disease: Chronic kidney disease stage 5
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
UMOD P07911 uromodulin 3.1E-17 0.520 0.846
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 0.98 0.524 0.769
PTPRF P10586 protein tyrosine phosphatase receptor type F Enzyme 1.00 0.578 0.615
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846
PPP1R2C O14990 PPP1R2C family member C Enzyme modulator 0.478 0.846