Disease: Renal fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
WWTR1 Q9GZV5 WW domain containing transcription regulator 1 Enzyme modulator 0.94 0.529 0.615
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
UMOD P07911 uromodulin 3.1E-17 0.520 0.846
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNC P24821 tenascin C 1.3E-07 0.433 0.846
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TAZ Q16635 tafazzin Enzyme 0.73 0.477 0.808
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SEMA7A O75326 semaphorin 7A (John Milton Hagen blood group) Signaling 0.18 0.636 0.615
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846