Disease: Polycystic Kidney Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
WWTR1 Q9GZV5 WW domain containing transcription regulator 1 Enzyme modulator 0.94 0.529 0.615
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNC P24821 tenascin C 1.3E-07 0.433 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
TBPL1 P62380 TATA-box binding protein like 1 Transcription factor 0.38 0.506 0.846
TAZ Q16635 tafazzin Enzyme 0.73 0.477 0.808
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SPAG11B Q08648 Q6PDA7 sperm associated antigen 11B 2.8E-02 0.650 0.731
SPAG11A Q08648 Q6PDA7 sperm associated antigen 11A 7.0E-05 0.650 0.731
SLC9B2 Q86UD5 solute carrier family 9 member B2 Transporter 7.6E-06 0.890 0.269
SEC63 Q9UGP8 SEC63 homolog, protein translocation regulator Chaperone 2.1E-07 0.736 0.308
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTGER2 P43116 prostaglandin E receptor 2 G-protein coupled receptor 7.5E-03 0.597 0.731