Disease: Polycystic Kidney Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PKD3 polycystic kidney disease 3 (autosomal dominant) 0.760 0.308
MIR17 microRNA 17 0.459 0.846
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
PKHD1 P08F94 PKHD1 ciliary IPT domain containing fibrocystin/polyductin 1.2E-47 0.576 0.654
DYNC2H1 Q8NCM8 dynein cytoplasmic 2 heavy chain 1 Enzyme 1.1E-44 0.555 0.731
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
PKD2L1 Q9P0L9 polycystin 2 like 1, transient receptor potential cation channel Ion channel 1.6E-27 0.565 0.731
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
CFB P00751 complement factor B 4.7E-16 0.532 0.769
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
IFT88 Q13099 intraflagellar transport 88 7.1E-11 0.621 0.654
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
PRKCSH P14314 protein kinase C substrate 80K-H Enzyme 1.0E-07 0.674 0.538
TNC P24821 tenascin C 1.3E-07 0.433 0.846
SEC63 Q9UGP8 SEC63 homolog, protein translocation regulator Chaperone 2.1E-07 0.736 0.308
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885