Disease: Cystic kidney
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LAMA5 O15230 laminin subunit alpha 5 Enzyme modulator 6.5E-03 0.636 0.577
ADCY6 O43306 adenylate cyclase 6 5.8E-03 0.729 0.500
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808
GLS O94925 glutaminase Enzyme 0.96 0.489 0.808
CFB P00751 complement factor B 4.7E-16 0.532 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
AVPR2 P30518 arginine vasopressin receptor 2 G-protein coupled receptor 0.56 0.568 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
AQP2 P41181 aquaporin 2 Ion channel 2.5E-06 0.581 0.769
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
PDE1A P54750 phosphodiesterase 1A 1.4E-02 0.743 0.385
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769