Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
IL18 | Q14116 | interleukin 18 | 3.1E-02 | 0.365 | 0.923 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
CXCL12 | P48061 | C-X-C motif chemokine ligand 12 | 0.12 | 0.379 | 0.846 | |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
EPO | P01588 | erythropoietin | 1.1E-02 | 0.381 | 0.885 | |
POSTN | Q15063 | periostin | Signaling | 1.1E-09 | 0.428 | 0.885 |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |
AVP | P01185 | arginine vasopressin | Signaling | 7.4E-02 | 0.437 | 0.846 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 |