Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
TGFB2 | P61812 | transforming growth factor beta 2 | Signaling | 1.00 | 0.433 | 0.885 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |
SMAD2 | Q15796 | SMAD family member 2 | Transcription factor | 1.00 | 0.456 | 0.808 |
SKI | P12755 | SKI proto-oncogene | 1.00 | 0.503 | 0.808 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
STAT1 | P42224 | signal transducer and activator of transcription 1 | Nucleic acid binding | 1.00 | 0.399 | 0.885 |
SOST | Q9BQB4 | sclerostin | 0.87 | 0.474 | 0.808 | |
RUNX1 | Q01196 | RUNX family transcription factor 1 | Transcription factor | 0.65 | 0.425 | 0.808 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
PRKD1 | Q15139 | protein kinase D1 | Kinase | 6.6E-07 | 0.531 | 0.846 |
PRKCA | P17252 | protein kinase C alpha | Kinase | 0.37 | 0.440 | 0.846 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
PLG | P00747 | plasminogen | Enzyme | 1.0E-02 | 0.389 | 0.923 |
PKHD1 | P08F94 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin | 1.2E-47 | 0.576 | 0.654 | |
PGD | P52209 | phosphogluconate dehydrogenase | Enzyme | 0.99 | 0.576 | 0.769 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |