Disease: Kidney Failure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
IGAN1 IgA nephropathy 0.524 0.808
MIR21 microRNA 21 0.363 0.846
PKHD1 P08F94 PKHD1 ciliary IPT domain containing fibrocystin/polyductin 1.2E-47 0.576 0.654
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
UMOD P07911 uromodulin 3.1E-17 0.520 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
COQ8B Q96D53 coenzyme Q8B Kinase 2.8E-13 0.722 0.423
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
ITGA8 P53708 integrin subunit alpha 8 6.1E-13 0.641 0.577
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
NPHS2 Q9NP85 NPHS2 stomatin family member, podocin Enzyme modulator 7.2E-09 0.576 0.538
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
AQP2 P41181 aquaporin 2 Ion channel 2.5E-06 0.581 0.769
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ILK Q13418 integrin linked kinase Kinase 3.8E-05 0.503 0.769
PKD2 Q13563 polycystin 2, transient receptor potential cation channel Ion channel 1.7E-04 0.552 0.731
HAGH Q16775 hydroxyacylglutathione hydrolase 1.8E-04 0.729 0.462