Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PGD P52209 phosphogluconate dehydrogenase Enzyme 0.99 0.576 0.769
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
ALG9 Q9H6U8 ALG9 alpha-1,2-mannosyltransferase Enzyme 6.4E-04 0.644 0.654
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885