Disease: Diabetic Retinopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR133B microRNA 133b 0.555 0.808
MIR20B microRNA 20b 0.581 0.615
OCLN Q16625 occludin 8.6E-07 0.507 0.846
CLDN7 O95471 claudin 7 Cell-cell junction 2.9E-03 0.494 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PCSK2 P16519 proprotein convertase subtilisin/kexin type 2 Enzyme 1.00 0.663 0.462
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962